Sentence examples for reverse the modifications from inspiring English sources

The team says it's the first to establish a specific link between aberrant histone modification and mechanisms underlying lupus-like symptoms in mice, and they confirmed that a drug in the research stage, trichostatin A, could reverse the modifications.

Using this algorithm, we can safeguard the original video as we can reverse the modification process if proper authorization can be established.

Most of these rely on a similar strategy of blocking unmodified cysteines, then reversing the modification and labeling with a thiol reactive reagent that provides a means of detection.

The O-GlcNAc hydrolase (OGA) cleaves the glycosidic bond, thus reversing the modification.

Conjugation is reversible; specific proteases ensure regeneration of the modifier pool and regulate the PTM by reversing the modification, or remodeling the chains (Eletr and Wilkinson, 2014).

Indisputably, the cloning of Dolly has shown that the oocyte cytoplasm is able to extensively reverse the chromatin modifications associated with a differentiated state [ 3, 4].

HDACi reverse the epigenetic modifications, reactivate gene expression and cause apoptosis in vitro in different cell types including CLL specimens [ 23- 26].

The lysate was incubated at 90°C for one hour to partially reverse the formaldehyde modification of nucleic acids.

If a rapid correction of a hypoosmolar state then occurs, glial cells start to increase the production of organic osmolites and the intracellular ion content, in order to reverse the previous modification and regulate cellular volume [ 15].

Treatments to reverse the aberrant epigenetic modifications are currently under intensive preclinical and clinical investigations and are discussed below.

This therapy is based on reversing the epigenetic modifications that occur in tumor cells and re-establishing a normal epigenome.