Sentence examples for reverse the dysfunction from inspiring English sources

We hypothesised that blockade of C5a would reverse the dysfunction of the BBB and restore the immunological and endocrinological homeostasis in the septic brain.

Moreover, compound 4n did not exhibit any acute toxicity in mice at doses up to 1000 mg/kg, and could reverse the cognitive dysfunction of scopolamine-induced AD mice.

Further, our data may suggest that blocking the p42/44 MAPK cascade could preserve normal vascular reactivity and reverse the vascular dysfunction associated with heart failure.

For example, determine whether acute overexpression of O-GlcNAcase, which has been shown reverse some of the adverse effects of diabetes on cardiac function [14], would also reduce sarcolemmal FAT/CD36 levels thereby reverse the metabolic dysfunction.

Understanding the role of S-nitrosylation may help to develop strategies to prevent or reverse the vascular dysfunction of sepsis.

Therefore, new therapeutic targets that can reverse the cardiovascular dysfunction associated with endotoxic shock may offer a valuable alternative.

Intensive endurance training did not induce beneficial effects on EDR aorta in control group and did not reverse the vascular dysfunction induced by the diabetic condition.

In fact, the IgG immunoreactivity in the hippocampus and frontal cortex of mice treated with DOX beginning at ~11 months was indistinguishable from 9-month old rTg4510 mice, suggesting that tau suppression by DOX could slow and possibly reverse the BBB dysfunction in these mice.

In addition to its anti-arrhythmic properties, chronic VNS has been shown to reverse the contractile dysfunction and adverse remodelling associated with experimental HF [ 81– 84] and appears to be beneficial even when applied at subthreshold intensities insufficient to cause changes in HR [ 85].

The results of the study by Rungatscher and colleagues [ 1] for deep hypothermia suggest that levosimendan could potentially also be used to reverse the mild diastolic dysfunction that occurs in many patients during moderate hypothermia.

Co-treatment with CPA and H89 completely reversed the contractile dysfunction.