Sentence examples for reverse signalling from inspiring English sources

The high spine density we observed in proximal Purkinje cell dendrites in these mice suggests that Eph receptor signalling rather than ephrin reverse signalling suppresses spinogenesis.

FasL rather inhibited the proliferation, indicating a negative reverse signalling capacity of FasL.

Signalling through the EphB receptors is considered forward signalling and through the ephrin B ligands, reverse signalling [ 4- 7].

Under low glucose conditions, forward signalling by EphA inhibits insulin secretion, whereas under high glucose conditions, reverse signalling through ephrin-A ligands enhances insulin secretion [ 39].

Consistent with these findings, various crucial signaling components of the T cell receptor activation pathway were inhibited by FasL triggering and reverse signalling.

We are currently investigating signalling and proliferative capacities of T cells derived from homozygous FasLDeltaIntra mice to validate a co-stimulatory role of FasL reverse signalling.

The reverse signalled by Corbyn's victory has not just been political and organisational, but almost a rejection of a whole style of professional politics.

Ephrin-A5, in addition to signaling forward through its Eph cognate ligand, facilitates reverse signaling by forming compartmentalized microdomains [34].

APC express CD137 ligand as a cell surface transmembrane protein, and CD137 ligand can transduce signals into APC, a process known as reverse signaling.

Although they do not possess catalytic activity themselves, both classes of ephrin ligands can activate signal transduction pathways after interaction with Eph receptors (reverse signaling) [10].

Thus, similar to forward signaling through receptors of the TNF receptor family, reverse signaling through CD137 ligand also requires oligomerization which is consistent with previous studies [24].