Sentence examples for reverse signal from inspiring English sources

In this review we discuss how ephrins (Eph ligands) "reverse signal" through their intracellular domains to affect cell adhesion and movement, but the focus is on modes of action that are independent of SH2 and PDZ interactions.

But we can currently not exclude that the overall topology of the receptor is disrupted in ΔGPS nor can we exclude that N-terminal portions of the GAIN domain, the interspaced region between HRM and GPS (Araç et al., 2012), contributes to reverse signal.

(d) The soluble TNFR1 fragment (sTNFR1-Fc) interferes with mTNF/TNFR tethering, but stimulates a reverse signal through its intrinsic activity.

Effect of EphB4/EphrinB2 reverse signal on angiogenesis induced by Xuefu Zhuyu Capsule containing serum in human microvascular endothelial cell 1.

(a) In the control setting, tethering between mTNF and TNF receptors (TNFR) provides the structural basis for strain to elicit a reverse signal through mTNF that links to ERK1/2.

Both components communicate using a bidirectional flow of information, i.e. the feedforward stream is augmented by a reverse signal flow via feedback.

These phosphorylation events can regulate signalling partner associations and reverse signalling through the intracellular domain of ephrinBs36.

Figure 7: TNF reverse signalling in the myogenic response.

By demonstrating that mTNF utilizes a non-canonical reverse signalling mechanism to initiate myogenic signalling, we provide evidence that TNF reverse signalling drives critical cardiovascular functions in vivo.

(b) Etanercept (ETN) which lacks intrinsic activity, interferes with mTNF/TNFR tethering and hence, reverse signalling.

Davy, A., Aubin, J. & Soriano, P. Ephrin-B1 forward and reverse signaling are required during mouse development.