Your English writing platform
Discover LudwigExact(14)
Forward (screening for phenotype) and reverse (screening for activity against a selected protein) chemical genetics, by combining medicinal chemistry, biological screening and combinatorial synthesis techniques, has enabled us to address previously intractable problems.
It also conducted reverse screening of every passenger who got off a United flight that left San Francisco in that period, checking shoes and baggage at the various destinations.
Gene-specific primers were designed for polymorphic coding sequences of the seven candidate genes for reverse screening.
Reverse screening based on the polymorphic coding sequence of seven Fe homeostatic genes detected by denaturing high performance liquid chromatography (dHPLC) revealed MuFRO1, a mutant for OsFRO1 (LOsFRO14g36720).
For Fe toxicity screening, 4,500 lines were randomly chosen for forward screening while 500 pooled DNA libraries (representing 24 M1 plants per pool) from the M4 generation were used for reverse screening (Figure 1). Figure 1 Schematic view of mutant discovery for rice mutant tolerance to Fe toxicity by reverse and forward genetic screens of a large FN-treated population.
The Herbochip® technology reported here was basically a reverse screening method.
Similar(46)
Reverse screen was initiated among 192 M4 genomic DNA pools.
In fast neutron treated population, it is not uncommon to identify multiple mutated genes from reverse screen.
The reverse screen subpopulation recovered the highest average number of duplication events.
Furthermore, the reverse screen duplication events exhibited a remarkably large size compared to the forward screen and no-phenotype subpopulations.
This included the striking example of reverse screen mutant FN0170228, where duplication events spanned nearly all of chromosome 15.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com