Sentence examples for reversal loop from inspiring English sources

Our results demonstrate that the double chain reversal loop connectivity identified previously by our laboratory within the Tetrahymena telomere d(T2G4 4 quadruplex, is a robust folding topology, since it has now also been observed within the d(G2T4G2CAG2GT4G2T) quadruplex.

Thus, one molecule of r GGAGGUUUUGGAGG) folds into a modified quadruplex comprising a G G G G tetrad, a UUUU double-chain reversal loop and a G G(:A):G G(:A) hexad.

This observation further supports our hypothesis that T=Ts inhibit double-chain reversal loop formation.

On the basis of our previous knowledge from the hybrid studies, T=T is not preferred in a double-chain reversal loop.

(13, 21, 23) Hybrids can adopt two different folds positioning the double-chain reversal loop at the 3′ or 5′ terminus of the G-quadruplex.

The α-HL experiments determined that T=Ts disrupt double-chain reversal loop formation but are tolerated in edgewise and diagonal loops.

This hypothesis was further supported by examining the other folds of the human telomere sequence: propeller (all double-chain reversal loops) and basket (no double-chain reversal loops).

Under dehydrating conditions (5 M LiCl), the human telomere sequence can assume the propeller fold (all double-chain reversal loops) in the presence of K+.

The largest change was observed for the T=T-containing natural telomere sequence when the propeller fold (all double-chain reversal loops) was studied.

This hypothesis was further explored by examining the basket fold that does not have a double-chain reversal, and the propeller fold that has only double-chain reversal loops.

The propeller fold is formed in the presence of K+ and contains only double-chain reversal loops; it is also commonly observed in various promoter sequences that are capable of G-quadruplex formation.