Sentence examples for reversal in phenotype from inspiring English sources

Microarray analysis of non-cultured human qHSCs and in vitro aHSCs and rHSCs reveals that the global gene expression profile of rHSCs was still very similar to that of aHSCs, indicating that this reversal in phenotype is not substantiated by a thorough reprogramming at the transcriptional level.

We did not find a specific reversal phenotype in the present study but nevertheless asked whether a decrease in adult neurogenesis, possibly matching the observed alterations in water maze performance, might be found after THC or CBD treatment.

Together, these results demonstrated that the reversal in the vhp-1 RNAi phenotype is kgb-1-dependent and further suggested a post-developmental switch in the contribution of kgb-1, from beneficial (for cadmium and tunicamycin protection) to generally detrimental.

Thus, we conclude that Map3k4 expressed from either BAC transgene was sufficient to rescue the sex reversal phenotype in these homozygous mutant embryos.

We therefore asked whether we could detect the apparently less robust reversal phenotype in the Ccnd2−/− mice if we applied the specific setup, protocol and analysis employed before (Garthe et al. 2009).

Ruling out dependence on growth and reproduction led us to hypothesize that the reversal in the vhp-1 knock-down phenotype might have reflected age-associated changes in signaling by the two stress-activated protein kinases regulated by VHP-1.

In contrast, removing IWR1 did not result in the reversal of the phenotype.

These results suggest that the anti-tumor activity of CDF is mediated via re-expression of miR-200 which may potentially results in the reversal of EMT phenotype and could also lead to overcome drug resistance in PC.

To investigate if reversal of the epigenetic aberrations in the tumorigenic LA1-55n cells with 5-Aza-dC treatment was sufficient to induce changes in phenotype, we first examined its effects on cell proliferation.

Observation of EV-mediated reversal of malignant phenotype in colon cancer cells suggests EVs as a potential therapy for CRC.

Our results suggest that EVs isolated from normal colon cells can mediate the reversal of malignant phenotype in colon cancer.