Our findings reveal a class of disease-causing mutations that inactivate protein function by disrupting chaperone-mediated folding in vivo.
These features localize downstream of VH genes and are excised by recombination, revealing a class of cis-regulatory element that governs recombination, distinct from expression.
Still, Trump revealed a class of voters who weren't being served by Democrats, normal Republicans, or even Republicans on the libertarian end of the spectrum.
Our findings reveal a class of bifunctional chemical agents that can preferentially inhibit membrane-bound p97 to disrupt ER homeostasis and to induce tumor cell death.
This analysis revealed a class 1 integron with the typical 5'-CS and a complete dfrA5 gene cassette, but lacked the usual class 1 integron-associated 3'-CS due to the insertion of IS26 (Figure 2).
Preoperative airway examination revealed a class II Mallampati with a normal mouth opening and normal dentition, a thyromental distance of 6.0 cm and limited neck extension.
Further analyses revealed a class of intron-derived lncRNAs that depend on the snoRNA machinery at both ends for their processing (sno-lncRNAs) [ 15].
Additional monitoring of the association kinetics revealed a class of steady ligands whose preformed association to SLP65 in resting cells remained unaltered upon BCR activation.
The majority of the 3-year-olds in the present study revealed a Class I canine relationship; while, a Class II relationship was more frequent in children with an oral habit.
A series of genetic screens to uncover regulators of light-dependent development revealed a class of loci that, when mutated, confer a partially constitutively photomorphogenic (cop) or de-etiolated (det) phenotype (reviewed by von Arnim and Deng, 1996).
