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Not infrequently, study of non-mammalian model systems has revealed principles that were later found also to be true for mammals including humans, but were not as easily discovered in mammals [ 26].
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Estimates of absolute protein abundance also reveal principles for optimizing design.
Answering these questions is important for understanding biological catalysis in general, and revealing principles for designing small molecule inhibitors.
This study reveals principles for instruction on topographic map understanding that could be adapted to other layered maps (e.g., weather maps).
use a protein engineering approach to render a temperature-insensitive voltage-gated channel cold- or heat-responsive to reveal principles for temperature-gating and a plausible model for molecularly enabling this mode of environmental responsiveness.
Although the law was originally thought to reveal principles of language functioning [1], many have argued against its relevance [2] [7].
Li G-W, Burkhardt D, Gross C, Weissman JS: Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources.
Our study reveals principles of neural circuit organization and development that are of general significance.
Similarly, identifying preferences of those not willing to participate could reveal principles that might underlie, in part, their decision.
Together, these results reveal principles that integrate 3D enhancer organization with dynamic in vivo TF-DNA interactions that may play a key role in regulating stem cell pluripotency.
Yet, dosage balance at the protein level is obvious as demonstrated in Li G-W, Burkhardt D, Gross C, Weissman JS: Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources.
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