With this method, we systematically revealed functional GO modules, i.e., groups of functionally similar GO terms, via an optimization model and then ranked them by enrichment scores.
Gene targeting experiments in the mouse [ 15, 16, 17, 18, 19, 20, 21, 22] have revealed functional differences between true null and partial loss-of-function (hypomorphic) mutant alleles of BRCA genes.
Loss-of-function analysis and the use of a dominant repressor version revealed functional overlap among CESTA and its homologues and confirmed the role of CESTA in the positive control of BR-biosynthetic gene expression.
Gene Ontology classification of AS genes revealed functional assignment of these genes in many biological processes with diverse molecular functions.
Covariation analysis revealed functional interaction between these structures during pain stimulation and distraction, but not during pain stimulation per se.
In recent years, chromosome conformation capture-based approaches have revealed functional types of 3D genome organization at different levels.
The newly revealed functional bi-layer coating architecture can potentially be adapted, using synthetic materials, to considerably enhance the surface load-bearing capabilities of various engineering configurations.
Furthermore, stimulus-independent functional connectivity MRI analyses (fcMRI) revealed functional connectivity between STG and other temporal regions (including contralateral STG) and medial and lateral prefrontal regions.
Transient expression of SYP51 and SYP52 in protoplasts revealed functional redundancy in vesicle sorting to the vacuole, localization to the TGN and endocytic compartments, and an inhibitory effect on fusion when accumulated on the tonoplast (De Benedictis et al. 2013).
Its effects likely resulted from an increase in receptor responsiveness, because it revealed functional 5-HT2A5-HT2Areceptor-operatedreceptor-operatedrons, an effect mimicked by knockdown of PSD-95.
For rice, however, no genetic studies have revealed functional roles for any PRXs except rice 1 Cys-peroxiredoxin (R1C-Prx/Os1-CysPrxA), which acts as a dormancy regulator and an antioxidant, based on a study with transgenic plants of tobacco, an heterologous system, that constitutively express R1C-Prx (GenBank Accession Number C19186; Lee et al. 2000).
