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Epigenomic maps reveal enhancer elements unique to NRs relative to 2D systems.
From early experiments that defined and mapped the first enhancers to recent enhancer models of human disease, functional experiments in the mouse have played a central role in revealing enhancer biology.
Independent enhancer-reporter transgene analysis of nub-8 through nub-13 conserved sequence clusters (CSCs) reveal enhancer function in the third instar larvae during larval CNS development.
Kaaij, L. T. et al. DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus.
Integrating eQTL, mRNA co-expression, and Hi-C data analysis, we developed a computational method to infer causal enhancer-gene interactions, revealing enhancers of clinically actionable genes.
New research (often conducted, paradoxically, on captive dolphins) has revealed new cetacean capabilities.
Genome characterization of B. xenovorans LB400 revealed interesting catabolic capabilities.
In general, both the crude extracts revealed greater antioxidant capabilities than the fractions.
Experiments on the mouse enhancers reveal that enhancers active in different tissues can be separated by pairwise comparison using N2.
In vitro kinetic analysis revealed the capability of FadA thiolase on longer chain acyl-CoA.
We revealed the capability of PAD4 to use platelet MPs as substrate.
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