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All meta-analyses revealed efficacy of adjuvant corticosteroids to various abortive medications – indicating generalizability.
The pooled analysis, in contrast to individual reports, revealed efficacy of the 150-mg dose; however, efficacy with BID dosing was only present with the 600-mg dose.
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New fluorescent materials reveal tumor locations and potentially surgical margins [26], dynamic bioluminescence reveals efficacy of vascular disrupting agents [27] and radionuclides may be detected by optical imaging [28].
Following an initial clinical observation revealing efficacy of aminoglutethimide in a breast cancer patient by Ralph Cash et al. (1967), Richard Santen et al. (1974) systematically implemented aminoglutethimide in concert with glucocorticoid substitution in an attempt to achieve an effective medical adrenalectomy.
This appears important in the context of a study with DAC, since the available evidence suggests that combinations of this HMA with a second epigenetic drug and an inducer of differentiation may reveal efficacy that is superior to the HMA alone.
Studies of other biologicals employed as monotherapy mostly revealed similar efficacy as MTX and had generally less efficacy than combination therapy.
Additionally, mTOR inhibitors have revealed antitumor efficacy across other tumor forms, indicating that they exhibit anti-tumor efficacy by themselves, not only as adjuvants to other cancer therapies (Motzer et al. 2010, Yao et al. 2010).
Our case revealed the efficacy of surgery for P-AVMs.
Recently, many studies have revealed the efficacy of the SAFM compared to the TBFM, focusing on cephalometric measurements [13 15].
Our previous open-label study in children revealed the efficacy of cinnarizine, a calcium channel blocker, in migraine prophylaxis.
The research revealed the efficacy of the extraction procedures as well as the antiproliferative and anti-inflammatory effects of birch extracts.
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