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The present study also revealed dose range differences in acetaminophen-induced reductions in the uptake of 18F-BCPP-BF between the liver and kidney.
Testicular histopathology revealed dose dependent dysregulation of spermatogenesis and presence of necrotic debris in seminiferous tubules which was marginally improved with Se.
by β-glucan treatment (5, 25, 50 and 100 mg/kg, i.p .. Finally, the hippocampi of aforementioned treated animals also revealed dose dependent inhibition of AChE enzyme.
Immunofluroesence analysis revealed dose dependent expression of immunoreactive LDLR in liver (Fig. 3C); specifically, within 35 days of vector treatment, 60 to 70% of hepatocytes expressed immunoreactive LDLR following injection with 1×1012 GC/mouse whereas between 5 to 10% of hepatocytes expressed detectable LDLR at the lowest dose showing some metabolic improvement (i.e., 3×109 GC/mouse).
MTT assay revealed dose and time dependent increased cytotoxicity of GS in head and neck cancer cells (SCC4 and HSC2) as shown in Figure 1a and 1b respectively.
Although they were revealed dose dependant cytotoxic effect but the maximum examined concentration was found of less than 20%% and the IC50 going to be more than 10000 μg/mL, which is 200 times the higher concentrations examined.
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The XTT assay revealed dose-dependent cytotoxicity to cancer cell lines.
Ocular malformation ratings revealed dose-dependent CP-55,940 teratogenicity within the full range of dosages tested.
Biomechanical testing revealed dose-dependent, higher trends in all parameters tested at the 4- and 8-week time points, with minimal significant differences.
Tapping mode AFM images revealed dosing of the water with 6 mg/L of orthophosphate was beneficial in retarding the growth of copper by-products.
Histological analysis of the liver, using CD31/PECAM-1 staining, revealed dose-dependent severe dilation of the sinusoids upon CX-treatment, as well as increased staining intensity for CD31.
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