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The analyses revealed combinations of CEA + IL-8 and CEA + CRP to show the best screening performance for colon cancer reaching a sensitivity of 47% and 39% in the validation set, respectively.
Our novel multiplex biochip revealed combinations of CEA + IL-8 and CEA + CRP to show the best screening performance for colon cancer with 47% sensitivity, for early carcinomas with 33% sensitivity, and adenomas with 18% sensitivity at an overall specificity of 86%.
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Extended analysis of ChIP-seq data in HeLa cells including additional DNA binding proteins [12] and further sequence analysis approaches might however reveal combinations of features to better explain the observed binding of STAT1.
Factor analysis should reveal combinations of key metrics that can be used to monitor performance.
To determine the prevalence of multimorbidity in the adult population attending primary care in Portugal, to identify associated sociodemographic factors, and to reveal combinations of chronic health problems.
The main types of complaints addressed to Patients Advisory Committeess concern medical maltreatment (42%), availability (12%), encounters (12%) and monetary issues (7%), 2 but the complaints often reveal combinations of reasons for complaining.
This study aimed to determine the prevalence of multimorbidity in the adult population attending primary care in Portugal, to identify associated sociodemographic factors, and to reveal combinations of chronic health problems that in the future might benefit from directed care management.
Further statistical analysis has revealed typical combinations of indicator values for each UST.
The ESI-MS experiments revealed diverse combinations of species in all the measured systems (see Figure 4).
Discriminative regression revealed that combinations of low- and high-threshold tests had discriminative validity for previous back pain, but were inconclusive for lower-extremity pain.
Indeed, genome-wide studies employing chromatin immunoprecipitation (ChIP) and state-of-the-art high throughput sequencing technologies have revealed specific combinations of histone marks associated with functionally distinct genomic elements [6 9].
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