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These compounds had marked antiarrhythmic and hypotensive activities and revealed affinity for α1- and α2-adrenoceptors.
The revealed affinity between transferrin (Tf) and transferrin receptor (TfR) in both systems is very high, Kd values are in the order of nM.
Thirteen species revealed affinity to inversed (wet and cold) stands of beech (3) and maple hornbeam wood (4), four of them represented montane species, whereas five species clearly preferred thermophilous sites (1, 2, 5).
Equilibrium binding analyses revealed affinity constants (KD) of 170 ± 30 nM and 1.9 ± 0.2 μM for EhPAK4 and EhPAK5 PBDs, respectively, as well as a high degree of nucleotide state selective binding to EhRacC, typical of Rho GTPase/effector interactions.
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Phylogenetic analysis of two of the subunits (p21 and p29) revealed affinities to the euryarchaeal enzyme whereas p30 appeared divergent.
Predicted interactions were tested through SPOT arrays and in solution affinity measurements revealed affinities in the 1 500 nM KD range [ 89].
Molecular evidence gathered over the following years revealed affinities with the Dinozoa [ 8], and even suggested this group to be its closest extant taxon [ 9, 10].
Furthermore, binding studies have revealed affinities of FE@SUPPY for human A1R and A2AR in the micromolar range, severalfold lower than towards human A3R [ 10].
Binding studies performed by gel electrophoresis reveal affinity of the IHF mimic 8 to dsDNA containing the λ phage H′-binding site and also a tendency for bending dsDNA.
Barney is unusual in having a room of his own, for the works are generally arranged to reveal affinities between different artists.
The mix of artists runs from J. M. W. Turner to Andy Warhol; the juxtapositions reveal affinities across centuries and cultures (Glueck).
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