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Upon Wnt stimulation, phosphorylation of β-catenin by GSK3 undergoes "two-phase" dynamic change: GSK3 phosphorylation of β-catenin is sharply inhibited within 30 min, phosphorylation then returns to its initial level in 2 hours [ 16, 17] or achieve even higher level in 6 hours [ 17].
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Phospho-AKT (Ser473) decreased transiently 24 h after docetaxel treatment and returned to its initial level 3 days after treatment.
In 1931, Masserman calculated the rate of CSF formation in patients by measuring the time needed for the CSF pressure to return to its initial level following drainage of a standard volume of CSF by lumbar puncture [ 48].
It is worth noting that after the stimulation Bax returns to its initial steady state.
The drop returns to its initial position.
Therefore, the spring returns to its initial shape after two full turns.
The polymer is rechargeable and returns to its initial charge-discharge cycle capacity.
During the phase without stimulation, the skin becomes depolarized and returns to its initial polarization.
Increase of the hydroxide-ion concentration inside matrix by means of its NaOH pretreatment returns the activity of the catalyst to its initial level.
Cardiac reperfusion following ischemia/anoxia results in the return of complex I A/D equilibrium to its initial level (A/D ratio ≈ 9 7) indicating that reintroduction of oxygen causes re-activation of the D-form of the enzyme [23,24].
In the Langendorf rat heart model and mouse infarction model, reperfusion results in the return of complex I A/D equilibrium to its initial level, indicating that reintroduction of oxygen causes reactivation of the D-form of the enzyme [ 18, 32].
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