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Applying the same analysis looking at genes that were close to motif pairs formed by the primary motif and one secondary motif (Tables S1, S2, S3, S4) returned terms that, in some cases, were not returned when working with primary motifs only, which suggested that motif pairs may be functionally more discriminatory.
On average, more than three of the top 10 returned terms from MTI correspond to manual annotation, whereas KNN returns more than four matching terms.
In each of the three main GO classifications, i.e., biological process, cellular component, and molecular function, "cellular process", "metabolic process", "cell", "cell part" and "binding" terms were dominant among the returned terms.
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Gene ontology (GO) mapping returned many terms.
Comparative functional analysis on these two groups returned GO terms significantly enriched in the 4th quartile gene list.
From the total revenues, 50% is returned in terms of winning prizes, the first prize is approximately 120,000 EUR.
Of the 6,899 genes containing non-synonymous SNPs, 5,712 had human orthologs and 3,880 returned BP terms (67.9%).
The physical and geometrical interpretation of the hardening, dynamic recovery, and radial return terms from the proposed generalized equation are presented.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com