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According to these guidelines, "an antimicrobial therapy for established infections should be continued until resolution of clinical signs of infection occurs, including normalization of temperature and white blood cell count and return to gastrointestinal function" [ 1].
The guidelines of the Surgical Infection Society and the Infectious Disease Society of America state that "an antimicrobial therapy for established infections should be continued until resolution of clinical signs of infection occurs, including normalization of temperature and white blood cell count and return to gastrointestinal function" [ 1].
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These clinical observations suggest that Cr is imperative not only to cerebral function in the central nervous system, but also to gastrointestinal function and homeostasis.
Following abdominal surgery, the time to return of gastrointestinal function was reduced with epidural anaesthesia but there were insufficient data to comment on mortality [ 23].
These advantages include rapid return of gastrointestinal function, fewer complications, and a shorter hospital stay [6, 7].
Indeed, it has been reported that perioperative over-hydration significantly delays return of gastrointestinal function [ 52, 53].
They demonstrated a significantly earlier return of gastrointestinal function with a total laparoscopic procedure, but these beneficial effects were not observed with laparoscopically assisted colectomy.
Statistically significant differences in a faster return of gastrointestinal function and shorter hospital stay were identified in favor of laparoscopic-assisted resection.
Basse and coworkers [ 51] demonstrated that actions that support faster return of gastrointestinal function can reverse or reduce complications after abdominal surgery.
Improved outcome as demonstrated by faster return of gastrointestinal function, a reduction in post-operative complications and shortened hospital stay was demonstrated when using the oesophageal Doppler for goal-directed fluid administration (that is, targeting stroke volume and FTc to maximize CI) during major surgery [ 48].
Feeding and sedation strategies are expected to influence gastrointestinal function.
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