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Previous studies have indicated a decrease in pERK1/2 activation, with return to basal levels within 2 h after stimulation [13, 31, 32].
Cell lines expressing recombinant G-protein coupled receptors (GPCRs) are activated by specific ligands resulting in transient [Ca2+] rises that return to basal levels in 30 60 s.
In chilled fruits, the activity of PPO showed a large peak at Day 3 to later return to basal levels by Day 4 and remained low at Day 8 of being harvested (Figure 2B).
Thermoregulatory defense was evoked by subjecting the Iceman (and a cohort of typical controls) to a fMRI paradigm designed to generate periods of mild hypothermia interspersed by periods of return to basal core body temperature.
In response to 10% cyclic uniaxial stretch, JNK activity was only transiently elevated, followed by a return to basal level as the actin stress fibers became oriented perpendicular to the direction of stretch.
A return to basal levels of ERK phosphorylation was observed following 24 h of GDNF application.
TNFα in serum and the gastric mucosa return to basal level within 3 hr after injection of LPS [12], [13].
Moreover, the inhibitory effect of IL-7 on food intake lasted for 24 hours before return to basal food intake (data not shown).
We then calculated the time of maximal response and the time needed for cells to return to basal levels (Table 1).
Activity in the inhibitory motor neurons takes longer to return to basal level due to the duration of the slow EPSPs in these neurons, but does so eventually.
Extended time courses up to 120 minutes have shown that SLK activity does not return to basal levels observed at time 0 (not shown).
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