To investigate whether the return of myelin sheaths after LPC treatment represents genuinely remyelinated fibres, we performed electron microscopy on cerebellar slices, to measure G-ratios (Figs. 4A C).
In 2004, lysophosphatidylcholine (LPC) was used to demyelinate rat cerebellar slices, with the subsequent return of myelin sheaths suggestive of remyelination (Birgbauer et al., 2004).
We considered the possibility that the apparent return of myelin sheaths in our slice system represents myelination of previously unmyelinated nerve fibres.
As in demyelinating lesions in vivo, we show that OPCs in our slice system proliferate in response to demyelination, that macrophages are present to clear myelin debris, and that the return of myelin sheaths after demyelination represents compact myelin with characteristics of remyelination.
The last step in the sequence was returning the blade to its sheath after flicking the fallen opponent's blood off it.
A rigid 250 × 4 mm optical resectoscope was used with an outer sheath that allowed the return of the expansion medium and an internal one for irrigation and resection cavity with cutting and coagulation electrode.
I'm Libby GelmandWaxner, and, because of what happened with Hillary and my doubts about Melania's new campaign to battle lap creases on white-silk sheath dresses, I've decided to return to my position as America's most beloved and irresponsible film critic.
St John's Night, which a colleague once described to me as "wonderfully bonkers", looks like a piece of pure fantasy with its goblins, magic potions and mountain visions – yet there is a scathing realism in Ibsen's portrait of posturing poet who thinks he will return to his primitive roots by carrying a sheath-knife and restoring Old Norse.
Teixeira went 0 for 3 and scored a run in his season debut after a three-month recovery from a torn tendon sheath in his wrist, and Youkilis returned from a bulging disk in his back to go 1 for 4 with a run batted in.
