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Retrospective data indicate that immunoprofiling of T cell markers can be prognostic in colon cancer.
Both randomized trials and retrospective data indicate that systemic 5-fluorouracil/leucovorin (5-FU/LV) improves outcome.
Our retrospective data indicate improved survival, which might be attributed to the fact that in the INT0139 study patients received preoperative radiation treatment.
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Retrospective data indicated that evidence based guidelines were poorly implemented prior to admission to the study, e.g. only 31% of participants with a lower limb ulcer had an ABPI or duplex assessment in the previous 12 months.
Interestingly, preclinical and retrospective patient data indicate that cardiac glycosides also can reduce the growth of various cancers, including breast, lung, prostate, and leukaemia (Stenkvist, 1999; Lopez-Lazaro, 2007; Mijatovic et al, 2007; Khan et al, 2009).
Retrospective clinical data indicate that HER2 overexpression in advanced BC is associated with relative resistance to treatment with tamoxifen [ 69] and greater benefits from the use of an AI [ 70].
Most evidence, although based upon retrospective or pooled data, indicate that the patients then are best treated according to the pathological stage.
Retrospective study data indicated that levels of implementation of evidence based guidelines were generally low in the twelve months prior to admission to the study clinics.
We now provide definitive retrospective data that indicate that YB-1 expression in low-risk patients is strongly associated with a higher rate of breast cancer related deaths.
Take-home point: Even though this is a retrospective analysis with limitations, the data indicate an alarming increased risk of cardiac malformations with the use of ondansetron in the first trimester.
In conclusion, despite the small sample size and the retrospective nature of the study, our data indicate that lymph node status is the most important predictive marker of tumour response to preoperative treatment in rectal cancer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com