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For both studies (prospective and retrospective) data analyses were conducted using Stata version 11 [ 14].
In addition, the MPR is a proxy measure of adherence that is widely used in retrospective data analyses [ 13, 14].
For example, their findings were based on retrospective data analyses or the samples used were small [ 19– 219.
Retrospective data analyses were performed using the Anticoagulant Quality Improvement Analyzer (AQuIA), a software tool designed to analyze health plan data.
Randomized controlled trials (RCT), prospective non-RCT studies, and retrospective data analyses were included; surveys, reviews, editorials, case series and textbooks were excluded.
Other investigators using retrospective data analyses have also found relatively robust treatment persistence with the use of biologic DMARDs in the treatment of PsA [ 17, 18, 20].
Similar(51)
This is a limitation of retrospective claims data analyses in Switzerland where clinical data are not available.
The findings reflect the real-life use of TNF inhibitors without the limitations of a clinical trial and allow for a head to head comparison although the inherent limitations of retrospective claims data analyses do not allow for causal conclusions.
If we, in addition to measurement error for observed exposure, have missing values for many exposure measurements possibly due to excessive cost or lack of data in retrospective analyses, data analyses themselves face challenges that can not be overcome by standard approaches.
Furthermore, the study illustrates the value of retrospective data in analysing determinants of quality of life in older age.
Our study illustrates the heuristic value of a broader analytical framework, as well as the promise of retrospective data, in analysing determinants of stressful work.
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