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Sean's Cardify, a customer retention platform, participated in the Battlefield NY 2012 but afterwards decided to shift focus to a side project that became Tinder.
Editor's note: Mike Dudas is co-founder and Chief Revenue Officer at Button, the VIP customer acquisition and retention platform for the on-demand economy.
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To evaluate spatial memory retention, the platform was removed for a probe trial 24 hours after the last day of hidden platform training.
Contrary to our earlier report, these PRh rats displayed good retention of both platform locations.
Time spent in the target quadrant on the probe trial was shorter under all doses of propranolol when compared to vehicle group (all p <.001), indicating poorer retention of prior platform location.
Rats that received PRh lesions approximately 2 days after the last training session displayed impaired retention of the platform's location, whereas rats that received PRh lesions 4 weeks after training did not.
The control mice exhibited good retention of the platform location by the second probe trial at the end of training (day 10) when they showed a significant spatial bias for the target quadrant where their search times were significantly greater than those observed in each of the other quadrants (p<0.0005), while the PCP-treated mice showed no such bias for the target quadrant (Fig. 4D).
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In summary, the results from the water maze testing at P75 indicated that the PCP-treated mice still had subtle deficits relative to the control mice during acquisition and retention of the new platform location.
Holmes and colleagues (2010) reported that levels of 11β-HSD1 mRNA in mouse hippocampal CA3 pyramidal cells were inversely correlated with spatial learning and spatial memory retention in the hidden platform version of the Morris water maze.
We incorporated the suggestions of both reviewers regarding the use of instrument platform and retention time standards, and to avoid confusion, we refer to a novel manuscript which has been published after the first version of this article, but uses a similar nomenclature for a different protocol (Erde, J. et al. (2014).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com