Sentence examples for retention of functionally from inspiring English sources

One of the hypotheses that has been proposed to explain retention of functionally redundant paralogs during evolution is a contribution to gene dosage and, thereby, to the capacity of the pathway or process in which they operate (97, 98).

Thus, genome or large-scale duplications can result in step increases in complexity because of the co-ordinated amplification and subsequent retention of functionally related genes such as growth factors and their receptors or proteases and their substrates.

However, the selective pressures that caused the long-term retention of these functionally redundant paralogs remain elusive (1, 10).

Indeed, in the absence of transcriptional subfunctionalization, it would be hard to explain the retention of so many functionally identical VvSTS gene family members.

Thus, functionally relevant retention of intronic sequence might be a more general phenomenon than previously suspected.

This aspect of the model is validated by the retention of activity in the DMEΔNΔIDR1 mutant and the inclusion of functionally important residues within the region contributed by domain A. In addition, the model places the catalytic Asp1304 and Lys1286 in close proximity to the flipped abasic site.

This feature is clearly consistent with the theory of a selfish operon, in which operons are viewed as mobile genetic entities that are constantly disseminated via HGT, although their retention could be favored by the advantage of the co-regulation of functionally linked genes [ 34].

The retention of ohnologs and local duplicates is functionally biased and often reciprocal in many gene families: WGDs tend to retain transcription factors, whereas local duplicates tend to retain the genes functioning in stress response (Freeling 2009; Rodgers-Melnick et al. 2012).

Furthermore, we chose "liver genes" to contrast our data on pigmentation genes with another category of functionally related genes that is not expected to be under high selection for duplicate gene retention.

overview of functionally characterized genes in rice online database.

His research interests include thermomechanical properties of functionally graded materials.