The purpose of this study was to explore the relationship of postelective CD urinary retention and dose of spinal morphine.
Using a nonhuman primate model, our aims were to evaluate (1) whether fluid shifts were detectable in normoglycemic monkeys, (2) which fluid compartment changed, and (3) whether fluid retention was dose dependent.
This is consistent with the preservation of dosage balance through deletion of loci with high connectivity, and retention of dose-insensitive proteins on the cell surface.
Nanoparticle uptake, retention, and dose-dependent effects on viability were compared in wild-type and DOX-resistant ABC transporter over-expressing rat glioma C6 cells.
Dexmedetomidine increased MADB106 lung tumor retention (LTR) dose-dependently (50 300 microg/kg/day), mostly through suppressing NK activity, as indicated through in vivo selective NK-depletion studies, and ex-vivo assessment of NK cytotoxicity.
They demonstrated internalization of DOX-loaded nanoparticles in MCF-7 cells with sustained intracellular retention and dose-dependent antiproliferative activity in cancer cells.
In addition, clinical and preclinical studies show that administration of glucocorticoids, 17β-estradiol, and GABAergic neuroactive steroids or agents that enhance their synthesis can facilitate extinction and extinction retention, depending on dose and timing of dose in relation to these complex PTSD-relevant recovery processes.
The proposed model and the model for zinc currently recommended by the International Commission on Radiological Protection yield reasonably similar estimates of total-body retention and effective dose for internally deposited radioisotopes of zinc but much different systemic distributions of activity and much different dose estimates for some individual tissues, particularly the liver.
The present study was designed to explore the correlations between morphine dose, retention of morphine-induced conditioned place preference (CPP), morphine-induced changes in levels of DA and its metabolites in the NAc in expression and retention of CPP in Sprague Dawley male rats.
Dose retention efficiency and viable aerosol retention rate were calculated from the sampler titers to determine the efficiency of microbe retention in lungs of mice.B. anthracis, Y. pestis, and M. tuberculosis aerosols were sampled through the port.
