In poor countries, they often die or develop blindness, retardation, lung problems or cerebral palsy.
The resulting risk of mental retardation, eye problems, skeletal abnormalities and stroke can be reduced by a special diet and high doses of vitamin B6 or B12.
In Down syndrome, an extra copy of chromosome 21 results in mental retardation, heart problems, and other abnormalities.
In this patient with severe hypotonia and retardation, feeding problems did not relieve in the following year.
Rett syndrome (RTT) is a developmental disorder manifested by primarily neurological symptoms, such as motor disabilities, mental retardation, communication problems, epilepsy and breathing disturbances.
The early signs of congenital poisoning (i.e., mental retardation, movement problems, seizures, primitive reflexes, and speech difficulty) could be mistaken for some other disease and over-looked, especially in mild cases.
The CNS is disrupted by the elevated levels of BCAAs and α-keto acids, resulting in dysmyelination, cerebral edema, dystonia, coma, retardation, psychiatric problems and even death within weeks of birth (Friedrich et al., 2012).
Subjects 1, 2, and 4 had similar clinical histories, including severe psychomotor retardation, feeding problems, severe post-natal growth retardation, arched eyebrows, anteverted nares, and ulnar deviation of the hands (Table 1, Figure 1), which are features partially shared with Cornelia de Lange Syndrome (CdLS) and BOS, but they did not have the trigonocephaly that is characteristic of BOS.
People with phenylketonuria, a rare inherited disease that leads to mental retardation, can avert problems with a special diet low in proteins.
Ubiquitin also is involved in a rare inherited condition known as Angelman syndrome, which leads to mental retardation and movement problems.
Manipulated by specialists in the field of disabilities, they portray characters dealing with deafness, blindness, cerebral palsy, mental retardation or other problems.
