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Rett syndrome (RTT) is a developmental disorder manifested by primarily neurological symptoms, such as motor disabilities, mental retardation, communication problems, epilepsy and breathing disturbances.
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Exclusion criteria were apparent developmental disorder and severe mental retardation precluding communication and consistent cooperation.
No patient suffered from organic mental disorder, mental retardation or language and communication disorders.
Secondly, TDRD3 was found to interact with FMRP, the gene associated with fragile X mental retardation syndrome (U. Fischer, personal communication).
Regional anesthesia was not possible in the present case, as the patient had difficulty in communication because of mental retardation and a hearing problem.
A mean cut-off score of 27.7 (according to the Vineland-II manual on adults with moderate-grade mental retardation) was used to categorize participants into a low communication group (mean score, ≤27.7), and a high communication group (mean score, >27.7).
Mutual communication was difficult due to the patients' mental retardation, and she showed involuntary movement of her arms, joint rigidity, and scoliosis.
After a normal developmental period, girls show growth retardation, microcephaly, stereotypic hand movements, motor abnormalities, mental retardation and communication dysfunction.
The population under study involved subjects from a case-control epidemiological investigation on intrauterine growth retardation (IUGR) carried out in the greater area of Québec City during 2006-2008 (Letallois et al. 2009; personal communication).
Profound retardation.
criterion for mental retardation".
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