Sentence examples for retains stem cell from inspiring English sources

This results in tumors that are driven by a cellular subcomponent that retains stem cell properties.

Thus, Integrins are required in ISCs to ensure that only one of the daughter cells retains stem cell fate.

Division of an ISC gives rise to one daughter cell that retains stem cell fate and another daughter cell that becomes an enteroblast (EB).

In this scenario, the two daughter cells are placed in different microenvironments and only one daughter cell maintains contact with the basement membrane and retains stem cell fate.

The cancer stem cell hypothesis proposed that tumors are driven by a cellular component that retains stem cell properties, including self-renewal, tumorigenicity, and multilineage differentiation capacity [ 11, 12].

The cancer stem cell hypothesis predicts that the chemotherapy-resistant ALDHhigh cells should retain stem cell activity.

However, the proportion of undifferentiated colonies in the presence of active Akt is lower when compared to culture in the presence of LIF alone, suggesting that not every differentiated cell is capable of retaining stem cell like characteristics when exposed to active Akt in the absence of LIF [24].

The 'central cells' were more likely to retain stem cell capacity compared with the 'border cells'.

At least some of their progeny has to retain stem cell function in order to maintain the stem cell pool.

All these aspects are dynamically orchestrated in vivo in order to retain stem cell identity, guide cell fate determination and maintain stem cell pool.

In rodents, it remains controversial whether stem cell capacity resides exclusively in the As pool, or a fraction thereof, or whether Apair cells also retain stem cell activity.