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When extracted and purified directly from the bacterial outer membrane, it retains expression of the lipid motif.
In contrast, the cat FLA completely lacks the DQ subregion and the dog DLA retains expression of only a pair of DQA and DQB loci (Figure 4).
Therefore, one important goal of this study was to evaluate the immunogenic potential of a non-lipidated form of P6, which still retains expression of a T cell helper epitope.
However, the mdx mouse still retains expression of some COOH-terminal dystrophin isoforms.
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Tumor #200, from an Ink4a mouse, retained expression of Arf but did not express p53 protein.
Western blot analysis showed that transformed IAR-6-1 epithelial cells retained expression of epithelial E-cadherin and did not express mesenchymal N-cadherin (Figure S1).
The resultant cell lines express an HCEC-specific transcriptional fingerprint, and retain expression of the corneal endothelial temperature-sensitive potassium channel, suggesting that significant dedifferentiation does not occur as a result of these modes of immortalization.
However, apparently contradicting its role as a classical tumour-suppressor protein, colorectal cancer cells retain expression of the retinoblastoma tumour-suppressor protein (Rb); they express high levels of Rb compared with adjacent normal tissue, and loss or mutations of the RB gene are rare.
We hypothesised that the retained expression of AQP1 in this tumour may offer treatment potential to AQP1-expressing tumours.
Spheroids cultured in undifferentiated spheroids of 3 and 10 days retained expression of CD44, without expression of differentiation markers.
Seeded cells retain expression of the functional markers Na+/K+-ATPase and ZO-1 and constructs have biomechanical properties similar to those of normal corneas.
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