Sentence examples for retains domain from inspiring English sources
Our observation that UvrD1 647, which retains domain 2a, shows reduced affinity for single-stranded DNA provides fresh evidence for a role of the C-terminal region of UvrD in single-stranded DNA binding.
This protein lacks the RRM domain found in full-sized CstF64 proteins [ 34] but retains domains responsible for interactions with CstF77 and with factors that mediate transcription termination.
Comparison of the retained domains with those of the IOM revealed considerable overlap, but the IOM had one domain—"safety"—missing from our list.
For each dataset we retained domains where the PDB file could be downloaded and a classification could be found for the domain in SCOP v1.75.
De novo evolved proteins will initially have no domains which are shared with other genes, while duplicated genes would tend to retain domains of their parental genes [ 37].
The shorter measure has improved measurement characteristics, retains conceptual domains and may be save administration time.
We generated defined mutations in different UHRF1 domains that retained SRA domain-mediated binding to hemimethylated DNA substrate sites, TTD-mediated recognition of H3K9me3 and binding of DNMT1, but did not allow maintenance DNA methylation.
We retained 504 domain regions and 1,658 non-domain regions of genes that met our criteria of having at least five nonsynonymous and 5 synonymous variants for further analysis.
The CD4deltaTM plasmid expresses recombinant soluble human CD4 lacking the transmembrane domain but which retains the cytoplasmic domain that facilitates solid-phase binding assays (rsCD4, aa 1 395, 421 458).
Our results support the former hypothesis that positive selection has driven the adaptive evolution of the extracellular domain whilst functional constraint retains the intracellular domain by purifying selection.
Abundant domain shuffling at the origin of Metazoa resulted in a set of synaptic genes that have retained their domain organization throughout all metazoan lineages.
