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XTT is a tetrazolium salt that is reduced to a soluble orange-colored formazan product by mitochondrial succinate dehydrogenase, which retains activity in metabolically active cells.
An RNA comprising the two domains of the Tetrahymena thermophila group I intron catalytic core retains activity, and the 5.0 angstrom crystal structure of this 247-nucleotide ribozyme is now described.
Insertion of a tetracysteine-motif-containing peptide at a conserved position in Lyp's catalytic domain generated a mutant enzyme (Lyp-CCPGCC) that retains activity comparable to that of wild-type Lyp in the absence of added ligand.
It would be interesting to know whether the TCR complex retains activity over this time.
CD154 is a type II transmembrane protein that retains activity as a soluble trimer.
Biotinylated NMB-1 retains activity and binds selectively to peripherin-positive nociceptive sensory neurons.
Similar(33)
Highly active compounds also retained activity against H. capsulatum phagocytosed into P388D1 macrophages.
These compounds are active against wild type reverse transcriptase (RT) and retain activity against clinically important mutants.
Clearly, because a protein is active in a cultured cell assay, it cannot be assumed to retain activity in vivo.
The paclitaxel-loaded nanoparticles retained activity in cell lines in vitro.
Intermediate calculated values needed for the determination of the retained activity of CLEAs have been summarized.
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CEO of Professional Science Editing for Scientists @ prosciediting.com