For the construction of biosensing system consisting of such functional proteins, the development of techniques for assembling of proteins with retaining their functions even on a solid substrate is required.
Genes in the same pathway can retain their function in organisms separated by a billion years of evolutionary history.
Introduction of antibodies which retain their function into cells using a simple and easy method would be very useful for study of the intracellular events in living cells.
Level II of factors PGE1, l-arginine, phycicacid sodium, and Bivalirudin could inhibit the activation of platelets and enable them to retain their function.
In other disorders, qualitative studies have shown that patients use medications to retain their function [28], e.g. the overall expectancy among patients with rheumatoid arthritis was that the medication would minimize the personal impact of the disorder [29], and asthma patients described using medications in order to be able to live normally [28].
These cysteine-modified receptors retain their function and lead to preferential pairing, thus interfering with heterologous chain pairing between introduced and endogenous receptors [51].
It is likely that certain residues in certain positions are required for the function of the protein and the de novo design may be focused on the set of sequences which are more stable than the native ones, but in the vicinity of the native so that they retain their function.
However, several mutants might retain their function if they could escape the quality control system.
However, several questions remain: how long will these cells will retain their function?
In applying rigid rules, however, quality control sometimes discharges proteins that, even though defective, retain their function.
A further problem is how these transferred genes were accepted and how they retained their function in the recipient genome.
