Sentence examples for retaining the efficacy from inspiring English sources

These limitations, combined with susceptibility to P-gp-mediated drug resistance, have prompted the search both for third-generation anthracyclines and for alternatives to the anthracycline scaffold [11], to avoid such liabilities while retaining the efficacy of these broadly used drugs [16], [27], [28].

There is an urgent need to develop more efficient versions of CBT that require minimal professional assistance but retain the efficacy profile of clinic based CBT.

The latter is a relatively new technology that retains the efficacy for at least 3 years.

For an agonist, the fluorescent molecule must retain the efficacy of the parent ligand, and enough potency still to be pharmacologically useful.

We chose to study hydroxyethyl starch 130/0.4 which is a medium molecular weight starch in a balanced electrolyte solution designed to minimize tissue accumulation and coagulation dysfunction while retaining the hemodynamic efficacy of conventional starches.

Cell viability studies showed that the NOTA-Erlotinib conjugate retained the biological efficacy of the parent Erlotinib molecule.

In examining multiple new derivatives of ethidium, with literature precedent or novel, we have identified one, a 5-benzylic acid ethidium derivative that is synthesized in three steps as a single isomer, and completely retains the inhibition efficacy of the parent compound.

A truncated version of this protein has been developed (CBLB502) which retains the radioprotective efficacy and stability while lacking its immunogenic properties.

Besides the added capabilities, the scheme retains fully the efficacy of established finite-volume MPDATA formulations.

The bispecific virus retained the original oncolytic efficacy, while providing proof of concept for a strategy to counteract issues of resistance development.

However, we were unable to find any reports which would suggest that the candidate vaccines presently under development are using technology that can retain the potency and efficacy at elevated temperatures.