Two point mutants, coq5- 2 (CH83-B3) and coq5- 5 CH316-6BB) laC-methyltransferaseactivityvity and Q6 biosynthesis but retain steady state levels of Coq5 and other Coq polypeptides [15,16,29].
Previous work in yeast has shown that certain point mutations within or adjacent to conserved COQ5 methyltransferase motifs result in a loss of Coq5 methyltransferase function, but mutants harboring these alleles (coq5- 2, coq5- 5) still retain steady state levels of Coq5 protein [15,16].
When grown under either the low or high osmolarity regimes, osmosensing circuits within EPB30/pRD400 cells could tolerate a roughly 10-fold range in EnvZ-V5 levels while retaining steady-state signal output similar to MDG147/pEB5 cells.
To retain steady growth numbers, production costs were often over-reported when they did not meet state guidance, and vice versa when excess was produced, creating inaccurate statistics and error-laden financial reports.
Since IκBα is also a downstream target gene of NF-κB, we hypothesized that lapatinib still can induce IκBα degradation but the protein level of IκBα was retained at a steady state in lapatinib-treated clones due to de novo synthesis.
Calculations show that grain boundaries with size of 200 nm can rotate by ∼30° during ECAP, thereby generating and retaining a steady-state equiaxed structure.
There are mutations that cause substantial reductions in ATP hydrolysis but have only minor effects on in vitro DNA unwinding (e.g., mcm3KA [ 19]), whereas other mutations retain robust steady-state ATP hydrolysis but reduce in vitro DNA binding or unwinding (e.g., mcm6DENQ [ 19, 32]).
The dynamic behavior of an autothermal reactor with internal countercurrent heat exchange is represented by a relatively simple mathematical approximat which retains essentially all of the steady state and dynamic features of real reactors.
