Sentence examples for retaining sensitivity to from inspiring English sources
The PDK1-IFPC::IFPN-AKT1 complex was resistant to inhibition of PI3K upstream of AKT, as well as inhibition of the AKT PH domain, while retaining sensitivity to inhibitors that target the pathway downstream of AKT.
A dramatic PMX resistance was observed under these conditions, at comparable levels to those obtained with DMOG treatment, while retaining sensitivity to BTZ.
Our findings suggest that solid tumors harboring a hypoxic core of cell cycle-arrested cells may display antifolate resistance while retaining sensitivity to the chemotherapeutics bortezomib and doxorubicin.
The present results suggest that Leishmania parasites resistant to SbIII, MF or AMB in the field could be more prone at acquiring multidrug resistance to these antileishmanials, while retaining sensitivity to PARO.
We therefore propose to undertake the first outcome measures follow-up at week 4 (6 weeks after initiation of antidepressant treatment, or optimisation for continuing patients) to ensure sufficient time for likely treatment effects whilst retaining sensitivity to clinical change.
Within the tandem pore potassium channel family, TREK-1 is sensitive to the anesthetic gases Xe, N2O, and cyclopropane, while TASK-3 is insensitive to these gases while retaining sensitivity to the volatile anesthetics.
Basic research investigating the efficacy of trastuzumab-DM1 for HER2-positive breast cancer cell lines has found that trastuzumab-resistant cells retain sensitivity to trastuzumab-DM1 [7].
This work proposes a method of implementing priors that on one hand reflects the belief concerning the typical situation and on the other retains sensitivity to anomalies of the prescribed type.
It is unlikely that both mutations would occur simultaneously, but Bridgham et al. (2006) found that one of the mutations retained sensitivity to 11-deoxycorticosterone, meaning that this intermediate step would still be functional, though in a different way, and could still have been favored before the second mutation occurred (Fig. 1B).
The eyes are regressed, but retain sensitivity to light.
Our data show that although ESSC are resistant to standard cytotoxic agents, they retain sensitivity to YK-4-279.
