"Those that have thrived have developed strong partnerships, have been able to operate certain things at scale, but I think one of the real challenges is how to retain true independence and mobilise the voice of citizens at the same time as surviving financially".
These fluid gels can act as pourable viscoelastic fluids but retain true gel micro/nano structure.
Intuitively, (X_o) retains "true" negative examples under LCWA, i.e., those that have required q relationship of x but are not a match of x.
Our mass defect filter removes unwanted noise from LC-MS metabolomics datasets, while retaining true metabolites, and requires only a list of m/z and retention time values.
The bar chart in Figure 3 illustrates schematically the ability of each of the three pharmacophore filters, applied sequentially, to selectively remove false positives (decoys) out of the set of docked poses while retaining true positives (known actives).
To circumvent the problem of such extensive variation among proteins and HVRs, we focused on recently diverged proteins that still retain true homology.
To account for this variability, methods based on estimating parameters over "windows" have been successfully used to reduce sampling error while retaining true signal in studies aimed at identifying evidence of selection in populations [ 2- 5].
By using a sample of observations that are each considered as an estimate of the same phenomenon, as opposed to treating observations individually, sampling error may be markedly reduced, while retaining true signal.
But also, those of us who mourn Allison grieve for the loss of a woman who took her scientific voice and spoke her mind while retaining true personal grace, dignity and perspective.
Second, DDiMAP did not generate significant numbers of spurious variants, even at low frequencies, as evidenced by the complete lack of calls in some genetic regions while other regions from the same specimen show mutation rates >10% (see Additional file 4: Table AF1), demonstrating the ability of the filtering algorithms to remove low level process noise while retaining true signal.
