Sentence examples for retained stem cell from inspiring English sources

One of two possible models might therefore describe the regenerative response; a selective model, in which specific stem cell progeny are retained within the regenerated area at the expense of others; or a stochastic model, whereby the fraction of retained stem cell progeny within the regenerated tissue is proportional to their initial contribution (Fig. 3).

To determine whether 3 day spheroids, cultured under maintenance conditions alone, retained stem cell markers, we evaluated expression of stem cell markers (CD44, CD133, CD166) and common markers for osteogenic, adipogenic, and chondrogenic differentiation by staining for von Kossa, oil red O, collagen II, and aggrecan, respectively over an additional 10 day period.

Furthermore, it has been shown that adult HSPCs treated with UNC0638 retained stem cell-like phenotypes and function better than the untreated, suggesting a potential application of pharmacological inhibition of G9a in stem cell renewal.

More studies with a larger number of treated animals and longer time frames are necessary to enhance the amount of retained stem cells and to improve the amount of expressed muscle proteins, leading to a better therapeutic effect.

The cancer stem cell hypothesis predicts that the chemotherapy-resistant ALDHhigh cells should retain stem cell activity.

However, the proportion of undifferentiated colonies in the presence of active Akt is lower when compared to culture in the presence of LIF alone, suggesting that not every differentiated cell is capable of retaining stem cell like characteristics when exposed to active Akt in the absence of LIF [24].

The 'central cells' were more likely to retain stem cell capacity compared with the 'border cells'.

This results in tumors that are driven by a cellular subcomponent that retains stem cell properties.

At least some of their progeny has to retain stem cell function in order to maintain the stem cell pool.

Thus, Integrins are required in ISCs to ensure that only one of the daughter cells retains stem cell fate.

Division of an ISC gives rise to one daughter cell that retains stem cell fate and another daughter cell that becomes an enteroblast (EB).