The more stable dinaphthyl derivative (t1/2 = 125 min) (Entry 4, Table 3) was retained in pulmonary capillaries due to its high lipophilicity (cLog P = 6.47).
This technique is based on the formation of microbubbles that are normally retained by the pulmonary capillaries and therefore do not appear in the left heart [ 10].
Moreover, it has been shown that neutrophils can be retained in the pulmonary microvasculature due to their low deformability, resulting in a higher concentration than in the systemic circulation.
A parallel drop in the circulating platelet count was induced, which at first suggested the occurrence of activation of circulating platelets, with aggregates being retained in the pulmonary microvasculature.
34 However, since SHIP-deficient mice that undergo allogeneic BM transplant have a normal lifespan, 32 these retained features of pulmonary pathology are apparently not sufficient to progress to the fatal lung consolidation that occurs in germline, SHIP-deficient mice.
Women who experienced and survived a severe health condition during pregnancy, childbirth or postpartum, such as: hysterectomy, blood transfusion, ruptured uterus, retained placenta, HELLP syndrome, pulmonary embolism, renal failure, heart failure and pelvic abscess, are considered as near miss or severe acute maternal morbidity (SAMM) cases [ 24, 25].
A CT scan demonstrated the post-pneumonectomy cavity (Fig. 2), patchy contralateral pulmonary consolidation and retained intraabdominal packing.
If it is shown that supervised maintenance exercise programs ensure the benefits of pulmonary rehabilitation are retained, in terms of exercise capacity and quality of life, then such programs should be routinely instituted.
Their underlying conceptual approach is logical, involving a widely used and well-accepted particle dosimetry model [multiple-path particle dosimetry (MPPD)] to estimate deposited and retained mass doses in the pulmonary alveolar region of nanomaterial-exposed workers.
Thus, it is unfortunate that the authors made it a main point to estimate (although crudely and with some questionable assumptions) the dose of inhaled nanomaterials that is retained or accumulated on the pulmonary alveolar surface over a full working lifetime of 45 years of exposure to 1 mg/m airborne concentration.
