MSH6-deficient cells are unable to repair single base mismatches, whereas they retain proficiency to repair two, three and four base loops (Drummond et al, 1995; Risinger et al, 1996; Umar et al, 1997), thus, causing only mononucleotide repeat instability in tumours (Wagner et al, 2001; Plaschke et al, 2004).
He retained reasonable proficiency in Italian for the rest of his life, albeit reportedly with an "atrocious" accent.
Immune profiling of our series of patients with HER2-overexpressing BC demonstrated a retained immune proficiency at diagnosis [ 13].
In the absence of anthracyclines, trastuzumab and paclitaxel induced a high rate of pCR, exploiting the synergy between the immunomodulating properties of these drugs and the retained immunological proficiency of patients with HER2-overexpressing BC.
The likely retained immune proficiency of HER2+ patients is supported by an apparently unchanged cytokine profile, as sharpened by the comparison with serum cytokine levels of healthy women, which displays no significant differences.
Studies have shown that students from low-income families tend to lose on average two months of reading proficiency through the summer months, while those from middle-class families retain their proficiency levels or improve during summer vacation, Gallagher noted.
Also, it was decided that all of the speaking tasks would be retained in the proficiency test.
Middle proficiency group The general tendency is retained in the middle proficiency group.
However, this tendency is not retained in the high proficiency group, where SIM has the most significant influence on the item difficulty (p value =.005), followed by DWD (p value =.06), and RPD (p value =.95).
Peripheral vision is usually retained but MD can impair proficiency in performing most activities in daily living and can make it more difficult for people to live independent lives.
The final model in which these four minisatellite loci were retained remained significant, and its proficiency was further improved relative to the univariate models using MATR-2 or MATR-16 (χ = 15.14, p <0.01).
