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However, some variants retained functioning similar to the wild type.
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So, if ascorbic acid was widely available in the human primitive diet, then selection to retain functioning GULO would have been relaxed (Lahti et al. 2009).
This phenomena relates to the redundancy of biological systems which are to ensure that the system retains functioning inspite of the perturbations.
The super stability with retained function results from the "hydrophobic effect" of supramolecular self-assembly of peptides and drugs.
Her spine was crushed, and while she retained function in her arms, she has none in her lower limbs.
All other retained homeologs appear to be under purifying selection for retained function.
In all cases, the obtained conjugates retained functions of individual modules.
As with the Class II proteins, these may have retained functions in SCW regulation or, as with Class III Arabidopsis proteins, developed new functions.
Based on our knowledge of Neurospora telomere binding proteins, it is likely that Tbf1 end-capping in S. cerevisiae [ 25] is a remnant of an evolutionarily retained function.
"The premise of orthopedics is to restore alignment so you can retain function," says Lieberman.
And in both the mind-door and five-sense door processes, when the retaining function ceases, the mind reenters its inactive mode.
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