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After 72 h, there was no apparent difference between non-treated and treated WM 1158R cells, whereas WM 1158S still retained elevated SOCS 3 expression.
Only a handful of these genes retained elevated expression past GD19, consistent with hematopoietic stem cells migrating from the liver to populate other tissues after birth.
As shown in Table 2, we found 40 (44.9%) and 23 (25.8%) out of 89 breast cancer tissues retained elevated phosphorylation on residues S727 and on Y705, respectively.
Interestingly, all (100%) of breast cancers that expressed moderate to high level of AKT S473) concomitantly retained elevated phosphorylation on AKT(T308), indicating an in vivo clinical correlation between them.
Up to 86% of metastasised breast tumour (stage 4) retained elevated phosphorylation on both PDK-1 S241 PDK-1 S24108) whereand100% of stAKT 308nd 76% of stage 4 revealed moderate to high level of phosphorylation on p70S6K(T389) (Table 3).
We expect loci involved in drainage-specific adaptation to have retained elevated levels of differentiation between drainages in the face of human-mediated gene flow.
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While protease and elastase levels vary between PAO1 and PA14, PAHM4 seems to have reduced overall protease levels while retaining elevated elastase activity compared to PAO1.
One potential mechanism of retaining elevated HIF-1 α in both BRCA1 and basal-like may be the relative paucity of PHD3, which showed significantly lower expression in BRCA1 tumours.
On the other hand, duplicate genes that are retained experience elevated levels of purifying selection [ 62].
Everyone wanted immediate and easy access and egress to that congested part of the city and it was demonstrated in a city vote in favor of retaining the elevated freeway just three years prior.
At 15°C, lin-12(n676n930) retains mildly elevated lin-12 activity due to the presence of the n676 mutation.
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