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Wnt3a-treated cells retained a differentiated phenotype, irrespectively of Dll4 addition.
From the first in vivo passages, the M38 tumor has also retained a differentiated papillary structure that is evident both in primary s.c. tumors and lymph node metastases, but not in lung metastases which are solid and poorly differentiated.
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Equine tenocytes retained a more differentiated state when cultured as scaffold-free microtissue spheroids in low serum-containing medium supplemented with l-ascorbic acid 2-phosphate, insulin and transforming growth factor (TGF -β1.
Islamic banks are structured so that they retain a clearly differentiated status between shareholders' capital and clients' deposits in order to make sure profits are shared correctly.
An extended tumour latency period in excess of 3 weeks was observed in the resveratrol treatment groups, with the resultant tumours retaining a more differentiated morphology as compared with control animals [ 18, 39].
Similarly to cells obtained from colony-forming assays, Ddit3-transduced cells retained a GMP-like phenotype, while control cells acquired differentiated myeloid surface markers.
Mature SM is not terminally differentiated and retains a certain degree of plasticity allowing to assume two distinct phenotypes: a more proliferative and able to synthesize extracellular matrix (ECM) components (synthetic) or a more differentiated, expressing preferentially more mature SM markers.
In general, differentiated macrophages retain a significant capacity to phagocytose opsonized particles.
In addition, the ability to compare the original fibroblast line that iPS were derived from to fibroblasts subsequently derived from them, will help establish if these differentiated cells retain a normalcy to their cell of origin.
When well differentiated, they retain a low level of local and metastatic aggressiveness.
Moreover, the shFoxO-expressing neuronal PC12 cells retained their differentiated morphology even after 72 h of A β1-42 expoSupplementaryentary Figure S6).
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