Since the clinical meaningfulness of patient reported changes in visual problems associated with OH treatments has yet to be established or refuted, inclusion of the EFF scale can, at the very least, be considered an attempt to retain the face validity of the TSS-IOP to patients – who recognize this as the most important reason for taking their medication in the first place.
Methods identical to the predictive validity testing conducted for the original 9-item tool 7 were repeated using receiver operator characteristic curve analysis 39 and demonstrated that it was possible to remove three items of the original 9-item tool, yet retain the predictive validity of the 'at risk' patient subgroup (i.e. those classified as medium and high risk by the 9-item tool).
However, because respondents did not retain anonymity, the validity of the study might have been compromised by managers trying to push a political statement in their response.
But it lost the case because it tried to retain the right to contest the validity of the patent with a view to past damages.
Nonetheless, we elected to retain the fatigue item, until further validity studies are carried out to determine its ability to identify clinically relevant fatigue among medical students.
However, based on the results on the other tests of validity and reliability measures by sex we decided to retain the measures.
You must retain the milk.
In order to minimize the number of statistical comparisons and to retain statistical validity in the analysis of correlated serial measurements on the same subject over time, we determined relevant summary measures as recommended by Matthews, et al. [19] and performed statistical analyses on these summary measures.
Regarding these patients as a part of the source population from which case patients could arise prevents a general selection bias and retains the internal and external validity of our study [ 25].
In conclusion, this study showed that the EC IFN-γ release assay is likely to retain its validity for the diagnosis of LTBI among HIV positive patients, with the caveat that its sensitivity decreases with advanced immuno-suppression.
