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The matrix is derived from porcine dermis, and is processed to retain the native collagen (Type 1) and elastin structure.
BAC transgenes usually retain the native gene architecture including all cis-regulatory elements as well as the exon intron configurations.
Firstly, although human biopsy samples at different OA stages represent the real progression of OA and retain the native PCM and ECM, they also suffer from disadvantages such as small sample volume, limited sample quantity, and restricted location for sample collection.
Thus, the Au DENPs we synthesized would be expected to retain the native ability of the PAMAM dendrimer, allowing effective chemical modification with biologically active molecules [30].
Vaccine development against malaria is focusing largely on subunit technologies [9], where the major obstacles include difficulties to retain the native conformation of key antibody epitopes and the need for an effective but safe human-compatible exogenous adjuvant [10].
Here, we analyzed the changes in the light-scattering properties of isolated thylakoid membranes by recording the absorbance of their suspensions in the region 400 750 nm. Figure 1A, upper panel, shows the characteristic spectra from wild type, stn7, stn8 and stn7stn8 membranes resuspended in a buffer containing 5mM MgCl2, to retain the native grana and stroma lamellae structures.
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The spectroscopic results revealed that the immobilized Hb retained the native catalytic activity and conformation.
Ultraviolet-visible and Fourier transform infrared spectroscopic results indicated that Hb molecules in the composite film retained the native structure.
The challenging joint-preserving surgery that retains the native joint with an optimal function may benefit from these assistances.
A small GroEL-binding tag made it possible to perform all steps of the encapsulation under near physiological conditions while retaining the native conformation of the target protein.
Although the fragment retained the native conformation and affinity to a protective antibody, its vaccine efficacy and conformational stability were significantly reduced with respect to full-length OspA.
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