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Willis's pieces retain the mark of their time without being hostage to it.
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Cornerbacks will run Tuesday, but Tennessee Titans running back Chris Johnson — who set the 40-yard-dash combine record when he ran it in 4.24 seconds in 2008 — retained the mark for at least a few more days.
Nearly all genes that were marked by H3K4me3 at their TSSs in QSCs from young mice retained the mark with age, despite a modest decline of the normalized tag intensity around TSSs.
Whereas the vast majority of genes marked by H3K27me3 (including bivalent and H3K27me3 only) retained the mark with age in QSCs, the breadth of coverage was found to decrease at a subset of these genes, although the shifts were not associated with transcriptional changes.
This place, the opposite of Trude, is a constantly changing metropolis that retains the marks of its past, "a temporal succession of different cities," Calvino writes, "wrapped one within the other, confined, crammed and inextricable".
Forcibly restrained, she tore at her skin and bit her hand so hard she retained the marks for the rest of her life, before Jesus appeared to her in a vision and she grew calm.
Whereas Warsaw removed every possible sign of damage, Berlin retained the marks of many shrapnel blasts partly because money was scarce, and partly because guilt led many Germans to feel that Berlin's role in the war should never be forgotten.
The Antarctic climate suspends both healing and decay; a pat of butter will retain the knife marks of a previous century, and the tiniest cut stays open for months.
Interestingly, while more than half of lncRNAs possessing H3K4me3 in ES cells retain this mark, the majority of the bivalent lncRNAs in ES cells commit to either the active or repressive mark in NPCs and fibroblasts.
Together these results suggest that the amount of CENP-A protein required to define the centromere may be cell type, and context specific in mammalian cells, with undifferentiated hPSCs requiring less CENP-A protein to faithfully retain the centromeric epigenetic mark relative to fibroblasts (Fig. 6).
Most also retain the original mint marks that identify where they were minted, illustrating the Roman system of regional mints producing coins to a uniform design.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com