However, our results indicate that at longer survival time (6 weeks) the two populations behave differently: mice enriched for 3 weeks after BrdU injection and placed back to standard conditions for 3 more weeks retain enhanced survival of GCs, whereas the effect is not long-lasting on PGCs.
This finding highlights the potential of HEVs not only to regulate the navigation of lymphoid cells but also their ability to retain important survival factors for plasma cells.
Remarkably, Bcl-2 and Bcl-xL always retain pro-survival functions.
Bladder cancer survival rates observed in the late 1990s may therefore reflect a more aggressive spectrum of bladder tumours than those retained in survival analyses for the 1980s.
Mice lacking Myog fed normally, exhibited increased cage activity by 1 year of age, and retained normal survival over a 2-year period of observation.
Overall, a total of 84 samples (with 27 events and 57 patients who were alive) were retained for survival analysis (Table 1).
In this context, it has to be emphasized that treatment regiments were chosen independent of the E2F1 status (Additional file 1) and that E2F1 levels retained predictive survival significance in patients with and without different adjuvant treatments (Additional file 2).
By univariate survival analysis, high sHE4 levels significantly correlated with decreased overall survival, progression-free survival and disease-free survival, retaining their independent prognostic value on the poorly differentiated EC cohort.
The broad assumption is that most urban animals are still sufficiently wild to retain an instinct for survival.
yw dFatp het flies retain a statistically significant survival extension on a diet supplemented with excess palmitic acid (Fig. 2e,f; log-rank for males and females: P < 0.0001), or linoleic acid (data not shown; log-rank for males and females: P < 0.0001).
