Sentence examples for retain potency from inspiring English sources

Additionally, the monopyrrolinone inhibitors retain potency in cellular assays against clinically significant mutant forms of the virus.

HBY 097 makes a hydrogen bond with the thiol group of Cys181 that helps the drug retain potency against the Tyr181Cys mutation.

Furthermore, in vitro functional characterization indicated that all retain potency of the chimeric mAbs and have comparable activity to their respective marketed drugs daclizumab, bevacizumab, and infliximab.

Mehta et al. reported that vancomycin, ceftazidime and moxifloxacin prepared in single-use polypropylene syringes retain potency, sterility and stability up to 24 weeks when stored at 0 C or 80 C [60].

By compartmentalizing SCs into micro-niches, tissues gain precise control over morphogenesis and regeneration: some progenitors specify lineages immediately, whereas others retain potency, preserving self-renewing features established early while progressively restricting lineages as they experience dynamic changes in microenvironment.

A phenyl group at R (compound 22) demonstrated that it is possible to achieve selectivity and retain potency.

Tests have shown that the 15 million doses stored frozen since vaccinations stopped can be safely diluted to 75 million while retaining potency.

But none was able to play the substantial innings required against a Yorkshire attack that retained potency and variety despite Tim Bresnan's absence with a pectoral strain.

Lowering the log D by switching to the more polar imidazo[1,5-a] pyridine core significantly diminished 2C9/2C19 inhibition while retaining potency.

A Chloro substituent at the 2-position of 1a, compound 1d, retained potency against DNMT1, while N6 alkylation, compound 7a, conserved DNMT3b2 activity.

Another variant with seven of twelve mutations in the V segment reverted retained potency within threefold of that of the mature antibody.