Sentence examples for retain high activity from inspiring English sources

Owing to this difference, moxifloxacin may retain high activity against increasingly common pneumococcal strains bearing substitutions in topoisomerase IV due to the wide use of old derivatives.

Accordingly, TALENs mutated at the C-terminal domain to reduce non-specific DNA-binding energy still retain high activity and exhibit improved specificity [ 31].

The tolerance to single nucleotide substitutions suggested that the Tev-mTALEN could retain high activity on substrates with multiple substitutions in the DNA spacer.

At doses less than, or equivalent to, the LD10, isophosphoramide mustard retained high activity against cyclophosphamide-resistant L1210 and P388 leukaemias, but was less active against intracerebrally-implanted P388 leukaemia while cyclophosphamide produced a 4 log10 tumour cell reduction.

In the presence of organic solvents, detergents and different concentrations of NaCl, EstA retained high activity.

This mutant also showed a high increase in temperature stability (Tm was raised by 13 °C) and retained high activity towards cephalosporin C under standard assay conditions.

In contrast to other previously characterized cholesterol oxidases, this enzyme retains high activity in organic solvents and detergents at temperatures above 85 °C despite its mesophilic origin.

Most of the mutants still retained high activity on β-carotene, however, the F213L single mutant and the R203W/F213L double mutant that yielded the highest improvement for astaxanthin production showed decreased activity for canthaxanthin production.

It was found that the molecular weight distribution of the isotactic polymer could be controlled while retaining high activity, high isospecificity and high molecular weight only by changing the kind and/or amount of the Lewis bases.

The transposases encoded by foreign genes have retained high activity, indicating a continuous exchange of 7653R and MAFF303099 genetic information with other species.

The data obtained show that all three recombinant galactosidases retained high activity with considerably high amounts of these solvents; A. niger rlacA displayed the highest tolerance (Online Resource 1, Supplemental Fig.  S8).