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This finding suggests that the regulation of dFoxO translation by IRES may help retain essential cellular functions during Drosophila fasting.
Although the graft metabolism is reduced during hypothermia, with a prolonged time period in which the anoxic cells can retain essential metabolic functions, hypothermia may induce liver injury by dysfunction of the Na/K ATPase membrane pump [ 61, 62].
Thus, Boc and Gas1 retain an essential function in these tooth germs, independent of their role in midline development of the central nervous system and face.
De Gaulle retained the essential function of parliaments in a democracy namely, the right to criticize governments and to withdraw confidence in them.
Science thus retains an essential function.
To investigate this further we tried to create triple mutants containing msh2Δ, ulp2Δ and a mutation in either SUMO itself (pmt3Δ) or one of its E3-ligases (pli1Δ, or the nse2-SA allele that lacks SUMO ligase activity but retains the essential function for Nse2 in chromosome maintenance [ 89]).
Under federal law, the government is not allowed to spend money that has not been appropriated by Congress, and agencies are allowed to retain only employees who perform essential functions critical to public health or national security.
During a funding lapse, agencies can retain certain employees to perform only essential functions that in many cases are matters of public health or national security.
These analyses also highlight 25 groups of genes only found in animals that are highly retained in all their genomes, with essential functions linked to animal multicellularity.
Another, not mutually exclusive, possibility is that the mutant protein encoded by the sec63 st67 allele retains enough activity to support some essential functions of the Sec63 protein.
But as long as the two ohnologs complement for essential functions, both can be retained in the genome, a process we called "subfunctionalization" (Force et al. 1999).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com