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In spite of its short plasma half-life of the parent molecule, SU101 can be administered intermittently in animal tumor models and retain efficacy.
Equally, the ever expanding quantity of data which biobanks will collect and generate about a data subject means it is difficult to state that any anonymisation or pseudonymisation process will retain efficacy over time.
However, controversy exists as to tolerance to the anxiolytic effects with some evidence that benzodiazepines retain efficacy and opposing evidence from a systematic review of the literature that tolerance frequently occurs and some evidence that anxiety may worsen with long-term use.
Thus, the newer-generation fluoroquinolones are reported to retain efficacy in the treatment of ofloxacin-resistant cases.
Of particular interest is the development of thermotolerant strains that can both evade the host thermal response and retain efficacy in hot climates.
Our identification of PD0325901 and idarubicin, compounds known for their bioavailability, supports this hypothesis and is consistent with the necessity of chemical hits to retain efficacy over a number of days in fly food and following larval ingestion.
Similar(53)
After 10 years as the first-line antimalarial drug, has sulfadoxine-pyrimethamine retained efficacy in Malawi?
These results extend the existing deimmunization literature, in which reduced immunogenicity and retained efficacy are assessed independently of each other.
A method to prepare a self-healing, antimicrobial polymer coating that retains efficacy against Escherichia coli O157 H7 in the presence of organic matter is reported.
The lead "switch-control" inhibitor, DCC-2036, potently inhibits both unphosphorylated and phosphorylated ABL1 by inducing a type II inactive conformation, and retains efficacy against the majority of clinically relevant CML-resistance mutants, including T315I.
However it should not be disregarded as its efficacy was impressive; a single dose retained efficacy for up to four days.
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CEO of Professional Science Editing for Scientists @ prosciediting.com